Managing Drugs on the Forefront of Personalized Medicine: The Erbitux and Vectibix Story

Case Solution

Richard G. Hamermesh, Raju Kucherlapati, Rachel Gordon
Harvard Business School ()

In May 2007, Amgen Inc. (Amgen) received disappointing news from the European Medicines Agency (EMEA) that its drug Vectibix, which was developed to fight metastatic colon cancer, had been rejected. This was particularly surprising news, as a similar competitor drug had received approval several years earlier. Additionally, Vectibix received approval from the Food and Drug Administration in 2006. In additional studies, Amgen has found that Vectibix is โ€‹โ€‹only effective in the 60% of the population who have a particular genetic marker. Given this development, what should Amgen’s strategy for Vectibix look like in both Europe and the United States?

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